Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 8/20 | 0.34 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9636802 | 1.00 | PTGS1 (0.38) | PTGS1GSTK1MAPTPTGS2BLM | |
| SCHEMBL930369 | 0.87 | ACE (0.41) | PTGS1GSTK1MAPTPTGS2BLM | |
| SCHEMBL80875 | 0.82 | MAPT (0.50) | PTGS1GSTK1MAPTPTGS2BLM | |
| SCHEMBL69148 | 0.82 | MAPT (0.50) | PTGS1GSTK1MAPTPTGS2BLM | |
| SCHEMBL197221 | 0.82 | MAPT (0.50) | PTGS1GSTK1MAPTPTGS2BLM | |
| Ammonia Solution, Strong SCHEMBL19614515 | 0.80 | MAPT (0.48) | PTGS1GSTK1MAPTPTGS2BLM | |
| Ammonia Solution, Strong SCHEMBL19614510 | 0.80 | MAPT (0.48) | PTGS1GSTK1MAPTPTGS2BLM | |
| SCHEMBL16360193 | 0.79 | — | — | |
| SCHEMBL7574384 | 0.78 | MAPT (0.42) | PTGS1GSTK1MAPTPTGS2BLM | |
| SCHEMBL22361657 | 0.78 | MAPT (0.42) | PTGS1GSTK1MAPTPTGS2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272462-B1 | Process for preparing ursodeoxycholic acid derivates and their inorganic and organic salts having therpeutic activity. | Jago Research AG (CH) | 1992-06-10 | — | — | EP | disclosed |
| US-4865765-A | TREATMENT OF ALTERED BILIGENETIC FUNCTIONS AND LITHIASIS OR DYSKINESIA OF THE BILIARY DUCTS | JAGO RESEARCH AG (CH) | 1989-09-12 | — | — | US | disclosed |
| EP-0272462-A1 | Process for preparing ursodeoxycholic acid derivates and their inorganic and organic salts having therpeutic activity. | Jago Research AG (CH) | 1988-06-29 | — | — | EP | disclosed |