Logran

Logran

SCHEMBL7574427

CC(C)OC(=O)c1cc(-c2nn(C)c(C(F)(F)F)c2Br)c(F)cc1Cl.COc1nc(C)nc(NC(=O)NS(=O)(=O)c2ccccc2OCCCl)n1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7574492 0.92 KDM4E (0.34) MAPTKDM4ENPC1ALDH1A1
Chlorsulfuron SCHEMBL7586029 0.91 KDM4E (0.37) MAPTKDM4ENPC1ALDH1A1
Logran SCHEMBL7586532 0.91
SCHEMBL7587004 0.90 MAPT (0.33) MAPTKDM4ENPC1ALDH1A1
Prosulfuron SCHEMBL7585572 0.89 KDM4E (0.32) MAPTKDM4ENPC1ALDH1A1
Thifensulfuron-Methyl SCHEMBL7578217 0.85 EDNRA (0.33)
Iodosulfuron SCHEMBL7577796 0.85
SCHEMBL7580645 0.85 EDNRA (0.32)
Chlorsulfuron SCHEMBL7581763 0.84 KDM4E (0.33) KDM4ENPC1ALDH1A1
Prosulfuron SCHEMBL7580847 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MAPT 1092/4885KDM4E 1886/4885NPC1 4238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.