Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.45 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7581822 | 0.79 | ALDH1A1 (0.41) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL27278402 | 0.75 | AMY1A (0.47) | AMY1AMAPTLMNAKDM4EALOX15 | |
| SCHEMBL7579213 | 0.74 | NPC1 (0.50) | PYCR1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3175339 | 0.74 | AMY1A (0.53) | AMY1AMAPTLMNAKDM4EALOX15 | |
| SCHEMBL3175343 | 0.74 | AMY1A (0.53) | AMY1AMAPTLMNAKDM4EALOX15 | |
| SCHEMBL29761174 | 0.74 | AMY1A (0.53) | AMY1AMAPTLMNAKDM4EALOX15 | |
| SCHEMBL11744250 | 0.73 | AMY1A (0.56) | AMY1AMAPTLMNAKDM4EALOX15 | |
| SCHEMBL7572620 | 0.72 | NPC1 (0.56) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL19346343 | 0.71 | AMY1A (0.55) | AMY1AMAPTLMNAKDM4EALOX15 | |
| SCHEMBL25376731 | 0.71 | MAPT (0.52) | AMY1AMAPTLMNAKDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |