Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | S100A4 | P26447 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574755 | 0.84 | DHODH (0.33) | DHODHPDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8815055 | 0.84 | TAS1R3 (0.34) | DHODHPDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7575170 | 0.83 | PDE2A (0.33) | DHODHPDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7576312 | 0.83 | DHODH (0.32) | DHODHPDE2A | |
| SCHEMBL7577691 | 0.81 | DHODH (0.36) | DHODHPDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8815862 | 0.81 | MAPT (0.33) | DHODHTAS1R3TAS1R1TAS1R2CCNA2 | |
| SCHEMBL27293226 | 0.81 | DHODH (0.33) | DHODHCCNA2CDK2CCNA1 | |
| SCHEMBL8816506 | 0.81 | HSD11B1 (0.39) | DHODHPDE2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7573501 | 0.81 | DHODH (0.34) | DHODHPDE2AS100A4NAMPT | |
| SCHEMBL7575287 | 0.80 | NAMPT (0.31) | DHODHPDE2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | claimed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |