Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 0.49 |
| ▸ | THRA | P10827 | 9/20 | 0.49 |
| ▸ | LDLR | P01130 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6660048 | 0.92 | THRA (0.51) | THRBTHRA | |
| SCHEMBL6658283 | 0.90 | THRA (0.53) | THRBTHRA | |
| SCHEMBL6676816 | 0.89 | THRB (0.51) | THRBTHRA | |
| SCHEMBL6665060 | 0.88 | THRB (0.51) | THRBTHRA | |
| SCHEMBL6658992 | 0.87 | THRB (0.55) | THRBTHRA | |
| SCHEMBL6658278 | 0.87 | THRB (0.54) | THRBTHRA | |
| SCHEMBL6662517 | 0.86 | THRB (0.53) | THRBTHRA | |
| SCHEMBL6658807 | 0.86 | THRB (0.53) | THRBTHRA | |
| SCHEMBL6661525 | 0.85 | THRB (0.53) | THRBTHRA | |
| SCHEMBL6658953 | 0.84 | THRB (0.53) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049226-A1 | Oxamic acids and derivatives as thyroid receptor ligands | CHIANG YUAN-CHING PHOEBE (US) | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049226-A1 | Oxamic acids and derivatives as thyroid receptor ligands | OXER1, THRA, OXGR1 | THRB 4/4885THRA 2/4885LDLR 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.