Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GCGR | P47871 | 4/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
| ▸ | TYK2 | P29597 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423973 | 0.83 | AHR (0.57) | RAB9ADUSP3PTPN11MAPK1GCGR | |
| SCHEMBL2473835 | 0.81 | AHR (0.54) | PTPN11HTR2BPDE4DIDO1TP53 | |
| SCHEMBL24810004 | 0.79 | GCGR (0.47) | RAB9ADUSP3PTPN11MAPK1GCGR | |
| SCHEMBL1423572 | 0.79 | PIM1 (0.53) | RAB9ADUSP3PTPN11MAPK1GCGR | |
| SCHEMBL14744471 | 0.79 | IMPDH2 (0.49) | RAB9ADUSP3PTPN11MAPK1GCGR | |
| SCHEMBL13986222 | 0.79 | RAB9A (0.50) | RAB9ADUSP3PTPN11GCGRMAPK14 | |
| SCHEMBL6798083 | 0.78 | RAB9A (0.44) | RAB9ADUSP3PTPN11HTR2BPDE4D | |
| SCHEMBL2934398 | 0.77 | CYP2A6 (0.58) | RAB9AHTR2BPDE4DTP53MEN1 | |
| SCHEMBL7582709 | 0.76 | CYP2A6 (0.53) | RAB9AMAPK1ALDH1A1ABL1MAPT | |
| SCHEMBL27722896 | 0.76 | CYP2A6 (0.56) | RAB9AHTR2BPDE4DTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |