Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 16/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 14/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 11/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13671075 | 0.81 | BCHE (0.54) | SIRT2BCHEACHESIRT1SIRT3 | |
| SCHEMBL4386983 | 0.81 | BCHE (0.54) | SIRT2BCHEACHESIRT1SIRT3 | |
| SCHEMBL757490 | 0.81 | BCHE (0.54) | SIRT2BCHEACHESIRT1SIRT3 | |
| SCHEMBL757049 | 0.68 | CTSS (0.50) | SIRT2CTSLCTSS | |
| SCHEMBL13671074 | 0.68 | CTSS (0.50) | SIRT2CTSLCTSS | |
| SCHEMBL2118680 | 0.67 | CTSL (0.77) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL12109633 | 0.67 | CTSL (0.59) | SIRT2SIRT1SIRT3CTSLCTSS | |
| SCHEMBL13884485 | 0.65 | CTSS (0.58) | CTSLCTSS | |
| SCHEMBL1122463 | 0.65 | CTSS (0.58) | CTSLCTSS | |
| SCHEMBL14433709 | 0.65 | CTSS (0.58) | CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708755-B1 | TRANSGLUTAMINASE MEDIATED CONJUGATION OF PEPTIDES | NOVO NORDISK HEALTHCARE AG (CH) | 2012-03-21 | — | — | EP | disclosed |