Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 4/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298424 | 0.94 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTATMTDP1 | |
| SCHEMBL2485730 | 0.94 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTATMTDP1 | |
| Hydrochloric Acid SCHEMBL2483358 | 0.92 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTATMTDP1 | |
| SCHEMBL28529501 | 0.89 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTATMTDP1 | |
| SCHEMBL28987193 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL22215228 | 0.86 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTTDP1MEN1 | |
| SCHEMBL5954418 | 0.85 | MMP2 (0.55) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL5954420 | 0.85 | MMP2 (0.55) | ALDH1A1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL29927511 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTATMTDP1 | |
| SCHEMBL13282701 | 0.83 | POLB (0.67) | ALDH1A1KDM4EMAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |