SCHEMBL7575673

SCHEMBL7575673

O=C(CC(O)Cc1ccccc1)CC(O)Cc1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.76
TRPV1 Q8NER1 3/20 0.65
CYP1A2 P05177 1/20 0.54
CPA1 P15085 3/20 0.52
CPA3 P15088 2/20 0.52
CPB1 P15086 1/20 0.52
CPB2 Q96IY4 1/20 0.52
SRR Q9GZT4 2/20 0.50
EPHX1 P07099 1/20 0.50
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50
ALPL P05186 1/20 0.48
POLB P06746 1/20 0.48
ALPG P10696 1/20 0.48
MDM2 Q00987 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3085039 0.90 TRPA1 (0.69) TRPA1TRPV1CYP1A2CPA1CPA3
SCHEMBL10535065 0.87 TRPA1 (0.65) TRPA1TRPV1CYP1A2CPA1CPA3
SCHEMBL1861755 0.87 TRPA1 (0.65) TRPA1TRPV1CYP1A2CPA1CPA3
SCHEMBL6138407 0.87 TRPA1 (0.65) TRPA1TRPV1CYP1A2CPA1CPA3
SCHEMBL3103285 0.87 TRPA1 (1.00) TRPA1TRPV1POLB
SCHEMBL3089814 0.84 TRPA1 (0.81) TRPA1TRPV1
SCHEMBL28977372 0.83 TRPA1 (0.61) TRPA1TRPV1CYP1A2CPA1CPA3
SCHEMBL28148321 0.83 TRPA1 (0.61) TRPA1TRPV1CYP1A2CPA1CPA3
SCHEMBL3102740 0.82 TRPA1 (0.59) TRPA1TRPV1CYP1A2CPA1CPA3
SCHEMBL1833635 0.81 TRPA1 (0.55) TRPA1TRPV1CYP1A2SRREPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103596729-A Structural member for polishing 3M INNOVATIVE PROPERTIES CO 2014-02-19 CN disclosed
WO-2002094328-A2 DOUBLE-SIDED COATED FIBROUS WEB ABSORBENT ARTICLE BASF AKTIENGESELLSCHAFT (DE) 2002-11-28 WO disclosed