Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 3/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575685 | 0.77 | ALDH1A1 (0.36) | ALDH1A1CYP2C19 | |
| SCHEMBL5465572 | 0.75 | TDP1 (0.63) | ALDH1A1TDP1KMT2AMAPK1 | |
| SCHEMBL27819169 | 0.73 | POLB (0.46) | POLBGAANPSR1ALDH1A1PRKCA | |
| SCHEMBL3935097 | 0.72 | LMNA (0.56) | POLBMAPTTDP1RECQL | |
| SCHEMBL7580544 | 0.71 | CYP4F2 (0.54) | GAAALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL29049106 | 0.71 | POLB (0.44) | POLBGAANPSR1ALDH1A1PRKCA | |
| SCHEMBL17694457 | 0.71 | MEN1 (0.42) | POLBGAANPSR1BRD4PRKCA | |
| Hydrochloric Acid SCHEMBL29148798 | 0.70 | BRD4 (0.35) | POLBGAANPSR1ALDH1A1BRD4 | |
| Bromide SCHEMBL29148801 | 0.70 | BRD4 (0.35) | POLBGAANPSR1ALDH1A1BRD4 | |
| Iodide SCHEMBL29148799 | 0.70 | BRD4 (0.35) | POLBGAANPSR1ALDH1A1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002096913-A1 | SUBSTITUTED DI(HYDROXY/ALKOXY)SILICON PHTHALOCYANINES AND THEIR USES | GENTIAN AS (NO) | 2002-12-05 | — | — | WO | disclosed |