Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583043 | 0.82 | TACR1 (0.51) | TACR1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14832626 | 0.80 | CYP2C9 (0.71) | CYP2C9CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL2485948 | 0.79 | POLB (0.67) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13282701 | 0.79 | POLB (0.67) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3966246 | 0.78 | TACR1 (0.52) | TACR1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7575664 | 0.77 | ALDH1A1 (0.61) | POLBMEN1KMT2AHTTLMNA | |
| SCHEMBL16116373 | 0.76 | SMN1; SMN2 (0.43) | POLBSMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL1832140 | 0.75 | HDAC3 (0.48) | POLBTMPRSS4EPHX2SMN1; SMN2MEN1 | |
| SCHEMBL1012287 | 0.74 | ALDH1A1 (0.57) | POLBTMPRSS4EPHX2SMN1; SMN2MEN1 | |
| SCHEMBL1818894 | 0.74 | SMN1; SMN2 (0.49) | POLBTMPRSS4EPHX2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |