Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 11/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7575632 | 0.88 | ERBB2 (0.50) | ERBB2EGFRPAK1CSNK2BKDM4E | |
| SCHEMBL7585204 | 0.87 | ERBB2 (0.51) | ERBB2EGFRPAK1CSNK2BKDM4E | |
| SCHEMBL7585812 | 0.85 | ERBB2 (0.56) | ERBB2EGFRKDM4EMAPTMAPK1 | |
| SCHEMBL7584725 | 0.85 | ERBB2 (0.58) | ERBB2EGFRPAK1KDM4EMAPT | |
| SCHEMBL7851398 | 0.83 | EGFR (0.50) | ERBB2EGFRPAK1CSNK2BMAPT | |
| SCHEMBL7850948 | 0.80 | EGFR (0.47) | ERBB2EGFRPAK1CSNK2BMAPT | |
| SCHEMBL7854398 | 0.80 | NOS2 (0.51) | ERBB2EGFRCSNK2BMAPTMEN1 | |
| SCHEMBL7578264 | 0.80 | EGFR (0.57) | ERBB2EGFRPAK1CSNK2BHPGD | |
| SCHEMBL7844069 | 0.79 | EGFR (0.45) | ERBB2EGFRPAK1CSNK2BABL1 | |
| SCHEMBL7587325 | 0.78 | MAP4K4 (0.47) | ERBB2EGFRMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020082420-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020082420-A1 | Bicyclic heterocycles, pharmaceutical compositions containing them, their use, and processes for preparing them | PKD1, REN, CYP11B1 | ERBB2 2419/4885EGFR 1041/4885PAK1 1856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.