SCHEMBL7576401

SCHEMBL7576401

C=[C]C(CC=C)(CC=C)N=C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1826779 0.70
SCHEMBL8693788 0.67
SCHEMBL11434828 0.64
SCHEMBL28428940 0.64
SCHEMBL9464502 0.64 HTT (0.37)
SCHEMBL2030245 0.61
SCHEMBL4366194 0.59
SCHEMBL30912804 0.58
SCHEMBL28484366 0.58 TRPA1 (0.30)
SCHEMBL20611431 0.57 MAPT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403197-B1 Polymer polyol compositions containing a grafted polyol-polyacrylate dispersant ARCO CHEM TECH (US) 1996-08-28 EP claimed
EP-0403197-A2 Polymer polyol compositions containing a grafted polyol-polyacrylate dispersant ARCO Chemical Technology, L.P. (US) 1990-12-19 EP claimed
EP-0986522-B1 CEMENT COMPOSITION ARCO CHEM TECH (US) 2002-03-13 EP disclosed
EP-0986522-A1 CEMENT COMPOSITION ARCO Chemical Technology, L.P. (US) 2000-03-22 EP disclosed
WO-1998055421-A1 CEMENT COMPOSITION ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1998-12-10 WO disclosed
US-5725654-A CEMENTS AND ADDITION POLYMERS ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1998-03-10 US disclosed
EP-0403197-B1 Polymer polyol compositions containing a grafted polyol-polyacrylate dispersant ARCO CHEM TECH (US) 1996-08-28 EP disclosed
US-5321077-A High stability ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1994-06-14 US disclosed
US-5194493-A Addition-condensation copolymer of polyether and isocyanate containing polycarbon ARCO CHEMICAL TECHNOLOGY, L.P. A PARTNERSHIP OF DE 1993-03-16 US disclosed
EP-0403197-A2 Polymer polyol compositions containing a grafted polyol-polyacrylate dispersant ARCO Chemical Technology, L.P. (US) 1990-12-19 EP disclosed