Primisulfuron

Primisulfuron

SCHEMBL7576485

CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CCS(=O)(=O)c1cccnc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1.O=C(Nc1nc(OC(F)F)cc(OC(F)F)n1)NS(=O)(=O)c1ccccc1C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TTR P02766 1/20 0.41
PPOX P50336 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 3/20 0.32
TBXA2R P21731 3/20 0.32
ALDH1A1 P00352 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
LMNA P02545 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
UGCG Q16739 2/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
CCR6 P51684 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7590931 0.95 TDP1 (0.46) MEN1KMT2ATTRPPOXTDP1
Primisulfuron SCHEMBL7588746 0.94 MEN1 (0.36) MEN1KMT2ATTRPPOXTDP1
Primisulfuron SCHEMBL7587599 0.94 MEN1 (0.39) MEN1KMT2ATTRPPOXTDP1
Primisulfuron SCHEMBL7588080 0.93 MEN1 (0.35) MEN1KMT2ATTRPPOXTDP1
Primisulfuron SCHEMBL7580722 0.93 MEN1 (0.35) MEN1KMT2ATTRPPOXTDP1
Primisulfuron SCHEMBL7588901 0.93 TDP1 (0.42) MEN1KMT2ATTRPPOXTDP1
Primisulfuron SCHEMBL7576156 0.92 TDP1 (0.48) MEN1KMT2ATTRPPOXTDP1
Rimsulfuron SCHEMBL7581924 0.92 MEN1 (0.42) MEN1KMT2ATTRPPOXTDP1
Primisulfuron SCHEMBL7587423 0.91 TDP1 (0.40) MEN1KMT2ATTRPPOXTDP1
Lactofen SCHEMBL7590183 0.91 TDP1 (0.40) MEN1KMT2ATTRPPOXTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885KMT2A 2099/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.