Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7585608 | 0.89 | APAF1 (0.32) | MEN1MAPTKMT2AUSP2ALOX15 | |
| SCHEMBL7574850 | 0.79 | SMAD3 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2SMAD3 | |
| SCHEMBL5059324 | 0.62 | SMAD3 (0.35) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1648180 | 0.62 | MAPT (0.59) | MEN1MAPTKMT2AUSP2ALOX15 | |
| SCHEMBL18468249 | 0.62 | MEN1 (0.52) | MEN1MAPTKMT2AUSP2ALOX15 | |
| SCHEMBL8492599 | 0.62 | MAPT (0.52) | MEN1MAPTKMT2AUSP2ALOX15 | |
| SCHEMBL7584565 | 0.62 | ALDH1A1 (0.41) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16108072 | 0.60 | MEN1 (0.50) | MEN1MAPTKMT2AUSP2ALOX15 | |
| SCHEMBL8495682 | 0.60 | KMT2A (0.47) | MEN1MAPTKMT2AUSP2ALOX15 | |
| SCHEMBL20478946 | 0.60 | KMT2A (0.47) | MEN1MAPTKMT2AUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | NQO2, NQO1, NDUFA7 | MEN1 1235/4885MAPT 3354/4885KMT2A 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.