Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.53 |
| ▸ | CCR5 | P51681 | 2/20 | 0.53 |
| ▸ | CCR8 | P51685 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | METAP1 | P53582 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | CBFB | Q13951 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322004 | 0.85 | NPC1 (0.69) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL31558882 | 0.84 | KDM4E (0.56) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL28115227 | 0.83 | CCR1 (0.52) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL29901533 | 0.83 | CCR1 (0.52) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL28406315 | 0.82 | CBFB (0.50) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL24870942 | 0.81 | CCR1 (0.50) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL12164875 | 0.81 | KDM4E (0.46) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL4337883 | 0.81 | CCR1 (0.50) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL21164394 | 0.81 | CCR1 (0.50) | CCR1CCR5CCR8NPC1ALDH1A1 | |
| SCHEMBL1016812 | 0.81 | SMN1; SMN2 (0.49) | CCR1CCR5CCR8NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |