Lactofen

Lactofen

SCHEMBL7576882

C#CC(C)Oc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl.CCOC(=O)C(C)OC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPOX P50336 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44
TTR P02766 1/20 0.44
KMT2A Q03164 1/20 0.44
FFAR1 O14842 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
MAPK1 P28482 1/20 0.31
PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flumipropyn SCHEMBL7587682 0.92 PPOX (0.44) PPOXTDP1MEN1TTRKMT2A
Flumipropyn SCHEMBL7580154 0.89 TDP1 (0.57) PPOXTDP1MEN1TTRKMT2A
Flumipropyn SCHEMBL7581215 0.87 PPOX (0.41) PPOXTDP1MEN1TTRKMT2A
Lactofen SCHEMBL7588209 0.86 PPOX (0.42) PPOXTDP1MEN1TTRKMT2A
Lactofen SCHEMBL7578370 0.86 TDP1 (0.40) PPOXTDP1MEN1TTRKMT2A
Flumipropyn SCHEMBL7587598 0.83 TDP1 (0.56) PPOXTDP1MEN1TTRKMT2A
Lactofen SCHEMBL8536001 0.81 MEN1 (0.66) PPOXTDP1MEN1TTRKMT2A
Lactofen SCHEMBL30606811 0.81 MEN1 (0.66) PPOXTDP1MEN1TTRKMT2A
Lactofen SCHEMBL30359837 0.81 MEN1 (0.66) PPOXTDP1MEN1TTRKMT2A
Lactofen SCHEMBL29462400 0.81 MEN1 (0.66) PPOXTDP1MEN1TTRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPOX 1/4885TDP1 1969/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.