Fomesafen

Fomesafen

SCHEMBL7576905

CS(=O)(=O)NC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].CS(=O)(=O)c1cc(C(F)(F)F)ccc1C(=O)c1cnoc1C1CC1.C[S+](C)C.O=C(O)CNCP(=O)([O-])O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 1/20 0.42
TTR P02766 1/20 0.42
PPOX P50336 1/20 0.42
KMT2A Q03164 1/20 0.42
THRB P10828 1/20 0.33
VDR P11473 1/20 0.33
SCN9A Q15858 3/20 0.32
SCN1A P35498 2/20 0.32
SCN5A Q14524 2/20 0.32
SCN2B O60939 1/20 0.32
SCN1B Q07699 1/20 0.32
FFAR1 O14842 1/20 0.31
MRGPRX4 Q96LA9 1/20 0.31
SCN4A P35499 1/20 0.31
SCN7A Q01118 1/20 0.31
SCN2A Q99250 1/20 0.31
SCN3A Q9NY46 1/20 0.31
SCN8A Q9UQD0 1/20 0.31
FLT1 P17948 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fomesafen SCHEMBL7588961 0.97 TDP1 (0.41) TDP1MEN1TTRPPOXKMT2A
Isoxaflutole SCHEMBL7578054 0.95 TDP1 (0.48) TDP1MEN1TTRPPOXKMT2A
Fomesafen SCHEMBL7583063 0.95 TDP1 (0.44) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7583979 0.93 TDP1 (0.47) TDP1MEN1TTRPPOXKMT2A
Fomesafen SCHEMBL7582126 0.92 TDP1 (0.43) TDP1MEN1TTRPPOXKMT2A
Isoxaflutole SCHEMBL7583695 0.92 TDP1 (0.44) TDP1MEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7582893 0.92 MEN1 (0.39) TDP1MEN1TTRPPOXKMT2A
Isoxaflutole SCHEMBL7584786 0.90 TDP1 (0.39) TDP1MEN1TTRPPOXKMT2A
Fomesafen SCHEMBL7585497 0.90 TDP1 (0.50) TDP1MEN1TTRPPOXKMT2A
Isoxaflutole SCHEMBL7574858 0.90 TDP1 (0.51) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.