⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516923 | 0.91 | — | — | |
| SCHEMBL7597911 | 0.81 | — | — | |
| SCHEMBL7555131 | 0.76 | — | — | |
| SCHEMBL6647131 | 0.74 | — | — | |
| SCHEMBL13097997 | 0.73 | HDAC6 (0.30) | — | |
| SCHEMBL3053816 | 0.68 | ABCB11 (0.49) | — | |
| SCHEMBL13654309 | 0.68 | ABCB11 (0.39) | — | |
| SCHEMBL1669641 | 0.67 | DRD1 (0.43) | — | |
| SCHEMBL1423328 | 0.67 | HRH3 (0.44) | — | |
| SCHEMBL3601295 | 0.65 | AGTR1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | disclosed |
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |