SCHEMBL7577329

SCHEMBL7577329

CCC(C)(C)c1ccc(OC=O)c(C(C)(C)CC)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 7/20 0.55
NPSR1 Q6W5P4 6/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
ALDH1A1 P00352 2/20 0.55
MAPT P10636 6/20 0.47
HTT P42858 3/20 0.47
UBE2N P61088 2/20 0.47
GLA P06280 1/20 0.47
MITF O75030 1/20 0.47
RAB9A P51151 4/20 0.43
RAD52 P43351 2/20 0.43
STAT3 P40763 1/20 0.43
RCE1 Q9Y256 1/20 0.43
APAF1 O14727 1/20 0.43
HSP90AA1 P07900 1/20 0.43
NOD2 Q9HC29 1/20 0.43
NPC1 O15118 3/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8943330 0.87 MAPK1 (0.45) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8678580 0.85 MAPK1 (0.52) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL4700880 0.84 MAPK1 (0.51) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL10809182 0.83 SHBG (0.40) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8089131 0.81 MAPK1 (0.49) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL7240794 0.81 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL8473986 0.81 MAPK1 (0.57) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11775938 0.81 MAPK1 (0.55) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL9396932 0.80 MAPK1 (0.56) MAPK1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL11776600 0.80 MAPK1 (0.59) MAPK1NPSR1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976740-B1 A synthesizing method for a 3-substituted-3-oxo-2-(2,4-oxazolidinedione-3-yl)propionic acid amide compound KONISHIROKU PHOTO IND (JP) 2002-09-25 EP disclosed
US-6204390-B1 REACTING A AROMATIC AMIDE COMPOUND WITH A OXAZOLIDIN-2,4-DIONE COMPOUND KONICA CORPORATION (JP) 2001-03-20 US disclosed
EP-0976740-A1 A synthesizing method for a 3-substituted-3-OXO-2-(2,4- Oxazolidinedion-3-YL)propionic acid amide compound KONICA CORPORATION (JP) 2000-02-02 EP disclosed
EP-0456163-B1 Silver halide photographic materials FUJI PHOTO FILM CO LTD (JP) 1997-08-06 EP disclosed
EP-0346899-B1 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 1994-08-31 EP disclosed
US-5223385-A Storage stable FUJI PHOTO FILM CO., LTD. (JP) 1993-06-29 US disclosed
US-5217857-A High speed color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1993-06-08 US disclosed
US-5084375-A Silver halide emulsions and couplers FUJI PHOTO FILM CO., LTD. (JP) 1992-01-28 US disclosed
EP-0456163-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-11-13 EP disclosed
US-5057408-A Coupler solvents FUJI PHOTO FILM CO., LTD. (JP) 1991-10-15 US disclosed
US-4906555-A Silver halide color photographic material comprising specified couplers and anti-fading agents FUJI PHOTO FILM CO., LTD. (JP) 1990-03-06 US disclosed
EP-0346899-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-12-20 EP disclosed
US-4879206-A HIGH SENSITIVITY; COLORFAST IMAGES FUJI PHOTO FILM CO., LTD. (JP) 1989-11-07 US disclosed
EP-0164030-B1 COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-09-06 EP disclosed
US-4851322-A CYCLOHEPTA/B/PYRROLE DYES FUJI PHOTO FILM CO., LTD. (JP) 1989-07-25 US disclosed
US-4840862-A HIGH SENSITIVITY AND STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1989-06-20 US disclosed
US-4767697-A PHENOL-TYPE CYAN DYE FORMING COUPLER, COUPLER SOLVENT, DISCOLORATION INHIBITOR OF DIHYDROXYBENZENE ETHER TYPE; COLORFAST FUJI PHOTO FILM CO., LTD. (JP) 1988-08-30 US disclosed
EP-0164030-A2 Color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-12-11 EP disclosed
US-4171975-A MAGENTA COUPLER AND AN AMIDE KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1979-10-23 US disclosed