Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | UBE2N | P61088 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089131 | 0.88 | MAPK1 (0.49) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6759089 | 0.87 | MAPK1 (0.42) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8678580 | 0.85 | MAPK1 (0.52) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5394859 | 0.85 | MAPK1 (0.47) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7577329 | 0.84 | MAPK1 (0.55) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7454444 | 0.83 | MAPK1 (0.45) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8473986 | 0.81 | MAPK1 (0.57) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL986848 | 0.80 | NPSR1 (0.39) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8655138 | 0.80 | MAPK1 (0.56) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10105923 | 0.78 | MAPK1 (0.55) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312337-B2 | Oxadiazoles and their manufacture | EASTMAN KODAK COMPANY (US) | 2007-12-25 | — | — | US | claimed |
| US-7268235-B2 | Method for preparation of N-pyrazolylamidoximes | EASTMAN KODAK COMPANY (US) | 2007-09-11 | — | — | US | claimed |
| US-20060074245-A1 | Method for preparation of N-pyrazolylamidoximes | EASTMAN KODAK COMPANY | 2006-04-06 | — | — | US | claimed |
| US-20060069262-A1 | Oxadiazoles and their manufacture | EASTMAN KODAK COMPANY | 2006-03-30 | — | — | US | claimed |
| US-6657083-B2 | Photographic couplers; acylation amine group in position 2 | EASTMAN KODAK COMPANY | 2003-12-02 | — | — | US | claimed |
| US-6613943-B2 | Intermediates for 4-substituted-2,5-diaminophenol derivatives as phenolic cyan couplers for color photography; deblocking the 2-acyl group by hydrolysis | EASTMAN KODAK COMPANY | 2003-09-02 | — | — | US | claimed |
| US-20030109716-A1 | 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM | EASTMAN KODAK COMPANY | 2003-06-12 | — | — | US | claimed |
| US-20030109753-A1 | 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2003-06-12 | — | — | US | claimed |
| US-6525219-B1 | Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation | EASTMAN KODAK COMPANY | 2003-02-25 | — | — | US | claimed |
| US-6476202-B1 | 5-acylamino-2-arylazo, nitro, or nitroso-4-substituted-phenol compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-05 | — | — | US | claimed |
| US-6280919-B1 | Photographic element containing a stable aryloxypyrazolone coupler and process employing the same | EASTMAN KODAK COMPANY | 2001-08-28 | — | — | US | claimed |
| US-6156490-A | Photographic element containing a stable aryloxypyrazolone coupler and process employing same | EASTMAN KODAK COMPANY (US) | 2000-12-05 | — | — | US | claimed |
| US-5354642-A | Polymeric couplers for heat image separation systems | EASTMAN KODAK COMPANY (US) | 1994-10-11 | — | — | US | claimed |
| US-5071994-A | Intermediates for positive working photographic compounds, analgesics; anti-inflammatory agents | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-10 | — | — | US | claimed |
| EP-0161626-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-05 | — | — | EP | claimed |
| US-4690889-A | SUBSTITUTED NAPHTHOL, HEAT AND LIGHT FASTNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1987-09-01 | — | — | US | claimed |
| EP-0161626-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-11-21 | — | — | EP | claimed |
| EP-2734180-A2 | COSMETIC AND/OR DERMATOLOGICAL COMPOSITION CONTAINING A MEROCYANINE DERIVATIVE COMPRISING SPECIFIC POLAR GROUPS CONSISTING OF HYDROXYL- AND ETHER-FUNCTIONALITIES | L'OREAL (FR) | 2014-05-28 | — | — | EP | disclosed |
| US-4073651-A | Image-forming layer containing silver halide emulsion and magenta coupler | MITSUBISHI PAPER MILLS, LTD. (JA) | 1978-02-14 | — | — | US | disclosed |
| US-3935015-A | Silver halide color photographic materials containing 3-anilino-5-pyrazolane couplers | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109753-A1 | 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them | CBR3, AADAC, HAAO | MAPK1 4592/4885NPSR1 405/4885SMN1; SMN2 4411/4885 |
| US-20030109716-A1 | 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM | AADAT, AAAS, ANXA7 | MAPK1 4456/4885NPSR1 757/4885SMN1; SMN2 3824/4885 |
| US-20060069262-A1 | Oxadiazoles and their manufacture | OXA1L, CYP1B1, OXER1 | MAPK1 1092/4885NPSR1 2618/4885SMN1; SMN2 1897/4885 |
| US-20060074245-A1 | Method for preparation of N-pyrazolylamidoximes | KCNH1, KCNJ2, KCNH2 | MAPK1 1689/4885NPSR1 980/4885SMN1; SMN2 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.