SCHEMBL757747

SCHEMBL757747

COc1c(OC)c2ccccc2c2ccccc12

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.82
ALDH1A1 P00352 3/20 0.82
SMN1; SMN2 Q16637 2/20 0.82
MAPK1 P28482 1/20 0.82
POLB P06746 1/20 0.54
CYP1A2 P05177 2/20 0.52
IDO1 P14902 2/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.48
MCL1 Q07820 1/20 0.45
CA4 P22748 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
SLC2A1 P11166 1/20 0.42
MAPT P10636 1/20 0.41
ABCG2 Q9UNQ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8859782 0.94 ALDH1A1 (0.82) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL52405 0.90 ALDH1A1 (1.00) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL29366129 0.90 ALDH1A1 (1.00) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
Iodide SCHEMBL5967814 0.88 ALDH1A1 (0.94) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL22788818 0.84 KDM4E (0.67) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL12486700 0.83 KDM4E (0.58) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL30003417 0.82 KDM4E (0.74) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL14349080 0.82 KDM4E (0.74) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL10022717 0.82 ALDH1A1 (0.71) KDM4EALDH1A1SMN1; SMN2MAPK1POLB
SCHEMBL1128021 0.82 KDM4E (0.64) KDM4EALDH1A1SMN1; SMN2MAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624392-B2 Molecular array generation using photoresist 10X GENOMICS, INC. (US) 2026-05-12 US disclosed
EP-4516394-A2 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2025-03-05 EP disclosed
EP-4481059-A2 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10x Genomics, Inc. (US) 2024-12-25 EP disclosed
EP-4405094-B1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS INC (US) 2024-12-18 EP disclosed
EP-4271511-B1 MOLECULAR ARRAY GENERATION USING PHOTORESIST 10X GENOMICS INC (US) 2024-10-09 EP disclosed
EP-4405094-A1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X Genomics, Inc. (US) 2024-07-31 EP disclosed
US-20240167077-A1 COVALENT ATTACHMENT OF SPLINT OLIGONUCLEOTIDES FOR MOLECULAR ARRAY GENERATION USING LIGATION 10X GENOMICS, INC. (US) 2024-05-23 US disclosed
US-20240076656-A1 HIGH DEFINITION MOLECULAR ARRAY FEATURE GENERATION USING PHOTORESIST 10X GENOMICS, INC. (US) 2024-03-07 US disclosed
US-20240060127-A1 METHODS AND SYSTEMS FOR LIGHT-CONTROLLED SURFACE PATTERNING USING PHOTOMASKS 10X GENOMICS, INC. 2024-02-22 US disclosed
WO-2024006799-A1 COVALENT ATTACHMENT OF SPLINT OLIGONUCLEOTIDES FOR MOLECULAR ARRAY GENERATION USING LIGATION 10X GENOMICS, INC. (US) 2024-01-04 WO disclosed
EP-1201638-B1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO (JP) 2004-06-23 EP disclosed
US-6677390-B1 CURABLE MIXTURES COMPRISING SENSITIZERS AND HALOGEN COMPOUNDS SUCH AS 4-CARBOXYMETHOXYPHENYL-2',4',6'-TRIMETHYLPHENYL-IODONIUM HEXAFLUOROPHOSPHATE, USED AS NONTOXIC ACID GENERATORS OR CATALYSTS; QUICK SETTING NIPPON SODA CO., LTD. (JP) 2004-01-13 US disclosed
US-6673457-B2 FOR RELEASEABLE COATING/FILM AGAINST PRESSURE-SENSITIVE ADHESIVES SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-01-06 US disclosed
US-6558871-B1 Photopolymerization initiator comprising at least one of diaryliodonium salt NIPPON SODA CO. LTD. (JP) 2003-05-06 US disclosed
US-20020106520-A1 Radiation-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-08-08 US disclosed
EP-1215254-A2 Radiation-curable organopolysiloxane composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-06-19 EP disclosed
EP-1201638-A1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO., LTD. (JP) 2002-05-02 EP disclosed
US-6313188-B1 USED AS CATALYSTS FOR CATIONIC PHOTOPOLYMERIZATION NIPPON SODA CO., LTD. (JP) 2001-11-06 US disclosed
EP-1106639-A1 PHOTOCURABLE COMPOSITION CONTAINING IODONIUM SALT COMPOUND NIPPON SODA CO., LTD. (JP) 2001-06-13 EP disclosed
EP-0927726-A1 PHOTOCATALYTIC COMPOSITION NIPPON SODA CO., LTD. (JP) 1999-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624392-B2 Molecular array generation using photoresist POLL, LIG4, LIG3 KDM4E 1169/4885ALDH1A1 189/4885SMN1; SMN2 3258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.