Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601685 | 0.93 | MEN1 (0.65) | CA1CA2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL7501950 | 0.87 | CA1 (0.81) | CA1CA2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL8513283 | 0.85 | CYP2C9 (0.55) | CA1CA2ALDH1A1MAPK1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5797806 | 0.85 | CA1 (0.79) | CA1CA2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL4573249 | 0.85 | KMT2A (0.71) | CA1CA2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL31198191 | 0.85 | UQCRB (0.71) | CA1CA2MAPK1FFAR4MEN1 | |
| SCHEMBL18031173 | 0.85 | UQCRB (0.71) | CA1CA2MAPK1FFAR4MEN1 | |
| SCHEMBL7571036 | 0.85 | CES1 (0.73) | CA1CA2ALDH1A1MAPK1FFAR4 | |
| SCHEMBL29118836 | 0.85 | KMT2A (0.71) | CA1CA2ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL27811906 | 0.85 | ALDH1A1 (0.71) | CA1CA2ALDH1A1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |