Pendimethalin

Pendimethalin

SCHEMBL7577750

CCC(CC)Nc1c([N+](=O)[O-])cc(C)c(C)c1[N+](=O)[O-].CP(=O)(O)CCC(N)C(=O)O.Nc1c([N+](=O)[O-])ccc(Oc2ccccc2)c1Cl

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
TTR P02766 1/20 0.45
ALB P02768 1/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
GRM4 Q14833 15/20 0.37
GRM8 O00222 14/20 0.37
GRM6 O15303 6/20 0.37
GRM7 Q14831 2/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pendimethalin SCHEMBL7583567 0.85 MEN1 (0.46) MEN1TTRALBTHRBKMT2A
Pendimethalin SCHEMBL22832167 0.85 GRM4 (0.46) GRM4GRM8GRM6GRM7
Pendimethalin SCHEMBL7581100 0.83 MEN1 (0.43) MEN1TTRALBTHRBKMT2A
Bifenox SCHEMBL7579712 0.82 TDP1 (0.53) MEN1TTRKMT2ATDP1GRM4
Acifluorfen SCHEMBL7578607 0.80 TDP1 (0.53) MEN1TTRKMT2ATDP1GRM4
Oxyfluorfen SCHEMBL7583192 0.80 MEN1 (0.42) MEN1TTRKMT2ATDP1GRM4
Aclonifen SCHEMBL7587215 0.78 TDP1 (0.49) MEN1TTRALBTHRBKMT2A
Fomesafen SCHEMBL7580633 0.78 MEN1 (0.45) MEN1TTRKMT2ATDP1GRM4
Pendimethalin SCHEMBL7586356 0.77 TDP1 (0.44) MEN1TTRTHRBKMT2ATDP1
Lactofen SCHEMBL7582267 0.76 MEN1 (0.43) MEN1TTRKMT2ATDP1GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT MEN1 4274/4885TTR 1945/4885ALB 1466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.