Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491100 | 0.84 | L3MBTL1 (0.40) | TP53RAB9ANPC1LMNAMAPT | |
| SCHEMBL8726663 | 0.81 | HPGD (0.38) | POLBRAB9ALMNAMAPTALDH1A1 | |
| SCHEMBL8813464 | 0.79 | HPGD (0.42) | MAPK1POLBABL1LMNAMAPT | |
| SCHEMBL8754760 | 0.78 | HSD17B10 (0.35) | MAPK1TP53POLBLMNAMAPT | |
| SCHEMBL8817757 | 0.77 | POLB (0.34) | POLB | |
| SCHEMBL16014081 | 0.76 | HPGD (0.39) | MAPK1POLBRAB9AABL1MAPT | |
| SCHEMBL8815593 | 0.76 | ABL1 (0.31) | MAPK1ABL1 | |
| SCHEMBL20932749 | 0.75 | MAP2K1 (0.45) | POLBRAB9ANPC1LMNAMAPT | |
| SCHEMBL7575375 | 0.75 | NR4A2 (0.46) | TP53LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8724282 | 0.74 | KMT2A (0.33) | LMNAKMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0609798-B1 | 4-Benzoyl isoxazoles and their use as herbicides | AVENTIS AGRICULTURE LTD (GB) | 2002-10-02 | — | — | EP | disclosed |
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| US-5721193-A | 2-oximinomethyl-1-phenyl-1,3-propanedione derivatives as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-02-24 | — | — | US | disclosed |
| EP-0713482-A1 | 2-OXIMINOMETHYL-1-PHENYL-1,3-PROPANEDIONE DERIVATIVES AS HERBICIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1996-05-29 | — | — | EP | disclosed |
| WO-1995004716-A1 | 2-OXIMINOMETHYL-1-PHENYL-1,3-PROPANEDIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 1995-02-16 | — | — | WO | disclosed |
| US-5374606-A | Pre- and postemergence | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-20 | — | — | US | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |
| EP-0609798-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |