Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7574482 | 0.82 | HPGD (0.33) | KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL8729992 | 0.80 | SMN1; SMN2 (0.36) | KMT2AHPGDSMN1; SMN2MEN1LMNA | |
| SCHEMBL8726570 | 0.77 | GPR119 (0.34) | KMT2AMEN1 | |
| SCHEMBL8724610 | 0.77 | ERCC5 (0.38) | KMT2AHPGDSMN1; SMN2MEN1LMNA | |
| SCHEMBL8145611 | 0.76 | KMT2A (0.43) | KMT2AHPGDSMN1; SMN2MEN1LMNA | |
| SCHEMBL8724619 | 0.75 | KMT2A (0.35) | KMT2AHPGDMEN1HTT | |
| SCHEMBL8389663 | 0.75 | SMN1; SMN2 (0.36) | KMT2AHPGDSMN1; SMN2MEN1LMNA | |
| SCHEMBL7577840 | 0.74 | MAPK1 (0.37) | KMT2AHPGDLMNAHTT | |
| SCHEMBL6746643 | 0.74 | ERCC5 (0.36) | KMT2AHPGDSMN1; SMN2MEN1HTT | |
| SCHEMBL8494921 | 0.73 | SMN1; SMN2 (0.35) | KMT2AHPGDSMN1; SMN2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625505-B1 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-10-28 | — | — | EP | disclosed |
| EP-0625505-A2 | 2-Cyano-1,3-dione derivatives and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-11-23 | — | — | EP | disclosed |