Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 6/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28656526 | 0.82 | MAPT (0.53) | TGFBR1MAPK14CYP1A2MEN1MAPT | |
| SCHEMBL10436783 | 0.81 | HTR2C (0.54) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10436792 | 0.80 | HTR2C (0.53) | MEN1MAPTKMT2AKDM4ENPC1 | |
| SCHEMBL27917128 | 0.80 | CYP1A2 (0.60) | TGFBR1MAPK14CYP1A2MAPTALDH1A1 | |
| SCHEMBL29699887 | 0.80 | CYP1A2 (0.60) | TGFBR1MAPK14CYP1A2MAPTALDH1A1 | |
| SCHEMBL1227713 | 0.80 | CYP1A2 (0.60) | TGFBR1MAPK14CYP1A2MAPTALDH1A1 | |
| SCHEMBL10436636 | 0.78 | HTR2C (0.49) | MEN1MAPTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL30487734 | 0.78 | CYP1A2 (0.58) | TGFBR1MAPK14CYP1A2MAPTALDH1A1 | |
| SCHEMBL28104399 | 0.77 | ACVR1 (0.50) | TGFBR1MAPK14CYP1A2ALDH1A1HPGD | |
| SCHEMBL10436769 | 0.77 | HTR2C (0.56) | MEN1MAPTKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773248-B1 | Polymers with heterocyclic side groups | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2002-10-02 | — | — | EP | disclosed |
| US-5668245-A | PHENYLENE POLYMERS WITH HETEROCYCLIC SIDE GROUPS | MAXDEM INCORPORATED (US) | 1997-09-16 | — | — | US | disclosed |
| EP-0773248-A1 | Polymers with heterocyclic side groups | MAXDEM INCORPORATED (US) | 1997-05-14 | — | — | EP | disclosed |