Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | ESRRA | P11474 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436769 | 0.86 | HTR2C (0.56) | HTR2CHTR2BKMT2AMEN1MAPT | |
| SCHEMBL10436783 | 0.82 | HTR2C (0.54) | HTR2CHTR2BKMT2AMEN1NPC1 | |
| SCHEMBL10436792 | 0.81 | HTR2C (0.53) | HTR2CHTR2BKMT2AMEN1MAPT | |
| SCHEMBL7577962 | 0.78 | TGFBR1 (0.50) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL10436634 | 0.78 | HTR2C (0.62) | HTR2CHTR2BKMT2AMEN1MAPT | |
| SCHEMBL6468321 | 0.77 | EGFR (0.54) | HTR2CHTR2BESRRAKMT2AMEN1 | |
| SCHEMBL2611896 | 0.76 | ALB (0.61) | HTR2BNPC1RAB9AKDM4EABCG2 | |
| SCHEMBL31731473 | 0.76 | TGFBR1 (0.50) | HTR2CHTR2BKMT2AMEN1MAPT | |
| SCHEMBL13043656 | 0.75 | ABCG2 (0.48) | RAB9AABCG2ALDH1A1AGPAT2POLB | |
| SCHEMBL10436626 | 0.75 | NPC1 (0.46) | HTR2CHTR2BKMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |