Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10436783 | 0.88 | HTR2C (0.54) | HTR2CHTR2BMEN1KMT2ANPC1 | |
| SCHEMBL10436792 | 0.87 | HTR2C (0.53) | HTR2CHTR2BMEN1KMT2ANPC1 | |
| SCHEMBL10436636 | 0.86 | HTR2C (0.49) | HTR2CHTR2BMEN1KMT2ANPC1 | |
| SCHEMBL7369475 | 0.85 | HTR2C (0.75) | HTR2CHTR2BMEN1KMT2ANPC1 | |
| SCHEMBL10436634 | 0.81 | HTR2C (0.62) | HTR2CHTR2BMEN1KMT2AKDR | |
| SCHEMBL10436626 | 0.79 | NPC1 (0.46) | HTR2CHTR2BKMT2ANPC1RAB9A | |
| SCHEMBL7577962 | 0.77 | TGFBR1 (0.50) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL22125125 | 0.76 | SMARCA2 (0.71) | MEN1KMT2ANPC1RAB9AEPHX1 | |
| SCHEMBL7375350 | 0.75 | HTR2C (0.74) | HTR2CHTR2BMEN1KMT2ANPC1 | |
| SCHEMBL2683478 | 0.73 | EPHX1 (1.00) | MEN1KMT2ANPC1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354994-A2 | Quinoline derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-02-21 | — | — | EP | disclosed |