SCHEMBL7578221

SCHEMBL7578221

C[SiH](CCC(F)(F)F)[Zr](Cl)(Cl)(C1c2ccccc2-c2ccccc21)C1c2ccccc2-c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC22A2 O15244 1/20 0.33
SLC22A3 O75751 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156230 0.77 ACHE (0.40) SLC22A2SLC22A3
SCHEMBL7586684 0.77 ACHE (0.40) SLC22A2SLC22A3
SCHEMBL3066419 0.74
SCHEMBL3644683 0.73 SLC22A2 (0.39) SLC22A2SLC22A3
SCHEMBL3073464 0.72
SCHEMBL3075033 0.72
SCHEMBL3067705 0.72
SCHEMBL3079615 0.71
SCHEMBL3070938 0.71
SCHEMBL3071043 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0729968-B1 Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins BASELL POLYOLEFINE GMBH (DE) 2002-09-25 EP disclosed
US-6365764-B1 METALLOCENE COMPOUNDS HAVING TWO FLUORENYL LIGANDS BRIDGED WITH A SINGLE SILICON OR GERMANIUM ATOM BASELL TECHNOLOGY COMPANY BV (NL) 2002-04-02 US disclosed
US-6180733-B1 OLEFIN POLYMERIZATION USING CATALYST COMPRISING THE PRODUCT OF REACTION BETWEEN A GROUP 4 OR 5 METALLOCENE COMPOUND AND AN ALUMOXANE, OPTIONALLY WITH ORGANOALUMINUM OR COMPOUND ABLE TO GIVE A METALLOCENE ALKYL CATION; ATACTIC POLYPROPYLENE MONTELL TECHNOLOGY COMPANY BV (NL) 2001-01-30 US disclosed
EP-0729968-A1 Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins Montell Technology Company bv (NL) 1996-09-04 EP disclosed