Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.33 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156230 | 1.00 | ACHE (0.40) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL6905614 | 0.80 | ACHE (0.42) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL7578221 | 0.77 | SLC22A2 (0.33) | SLC22A2SLC22A3 | |
| SCHEMBL3644683 | 0.73 | SLC22A2 (0.39) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL7195132 | 0.71 | ACHE (0.42) | ACHEBCHECHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL10181364 | 0.70 | ACHE (0.41) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL797345 | 0.69 | ACHE (0.44) | ACHEBCHECHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL156229 | 0.69 | ACHE (0.41) | ACHEBCHECHRM2HTR1AADRA2A | |
| SCHEMBL5549432 | 0.67 | CYP3A4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL5614359 | 0.67 | ACHE (0.41) | ACHEBCHECHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729968-B1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2002-09-25 | — | — | EP | disclosed |
| EP-0729968-A1 | Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins | Montell Technology Company bv (NL) | 1996-09-04 | — | — | EP | disclosed |