Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 9/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7059392 | 0.92 | PGR (0.38) | CHRNA7CHRNB2CHRNA4RECQLSMN1; SMN2 | |
| SCHEMBL7157879 | 0.89 | CHRNA7 (0.38) | CHRNA7CHRNB2CHRNA4ALDH1A1 | |
| SCHEMBL7225512 | 0.87 | PTPN1 (0.42) | CHRNA7CHRNB2CHRNA4RECQLSMN1; SMN2 | |
| SCHEMBL7062754 | 0.85 | CHRNA7 (0.41) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7060672 | 0.85 | CHRNA7 (0.39) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7060620 | 0.85 | CHRNA7 (0.41) | CHRNA7CHRNB2CHRNA4HPGDSMN1; SMN2 | |
| SCHEMBL7063522 | 0.85 | CHRNB2 (0.37) | CHRNA7CHRNB2CHRNA4HPGDSMN1; SMN2 | |
| SCHEMBL7061959 | 0.85 | CHRNA7 (0.39) | CHRNA7CHRNB2CHRNA4RECQLSMN1; SMN2 | |
| SCHEMBL7062714 | 0.84 | CHRNA7 (0.39) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL7062245 | 0.84 | CHRNA7 (0.39) | CHRNA7CHRNB2CHRNA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002015662-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |