SCHEMBL7579018

SCHEMBL7579018

O=C(O)c1c(F)c(O)c(F)c(F)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
DPP4 P27487 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALB P02768 1/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
GLRA3 O75311 1/20 0.33
GLRB P48167 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
CYP1A2 P05177 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29773954 1.00 ESR1 (0.39) ESR1DPP4CA12CA1CA2
SCHEMBL28924074 0.97 ESR1 (0.38) ESR1DPP4CA12CA1CA2
Water SCHEMBL9861421 0.97 ESR1 (0.38) ESR1DPP4CA12CA1CA2
SCHEMBL8375873 0.92 ESR1 (0.38) ESR1DPP4CA12CA1CA2
SCHEMBL721202 0.92 ESR1 (0.41) ESR1DPP4CA12CA1CA2
SCHEMBL31021584 0.89 DPP4 (0.36) ESR1DPP4CA12CA1CA2
Water SCHEMBL1285779 0.89 ESR1 (0.39) ESR1DPP4CA12CA1CA2
SCHEMBL9490372 0.89 ESR1 (0.34) ESR1DPP4
SCHEMBL9490363 0.89 ESR1 (0.34) ESR1DPP4
SCHEMBL8979014 0.87 ESR1 (0.40) ESR1MEN1KMT2ASMN1; SMN2CRHBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0271275-B1 TRIFLUOROHYDROXYAROMATIC ACID AND PREPARATION THEREOF UBE INDUSTRIES, LTD. (JP) 1991-11-27 EP claimed
US-4831190-A BACTERICIDE INTERMEDIATES UBE INDUSTRIES, LTD. (JP) 1989-05-16 US claimed
EP-0271275-A1 Trifluorohydroxyaromatic acid and preparation thereof UBE INDUSTRIES, LTD. (JP) 1988-06-15 EP claimed
JP-11255701-A None JP disclosed
JP-11255701-A None JP disclosed
JP-1006235-A None JP disclosed
JP-11286470-A None JP disclosed
JP-3232838-A None JP disclosed
JP-3232838-A None JP disclosed
JP-63264439-A None JP disclosed
JP-8134014-A None JP disclosed
US-4937377-A HEATING IN A SOLVENT SELECTED FROM DIMETHYLACETAMIDE, METHYL PYRROLIDONE AND QUINOLINE OCCIDENTAL CHEMICAL CORPORATION (US) 1990-06-26 US disclosed
US-4935541-A Preparation of 2,4,5-trifluorobenzoic acid by decarboxylation of 3,4,6-trifluorophthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1990-06-19 US disclosed
EP-0352123-A2 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use UBE INDUSTRIES LIMITED (JP) 1990-01-24 EP disclosed
US-4831190-A BACTERICIDE INTERMEDIATES UBE INDUSTRIES, LTD. (JP) 1989-05-16 US disclosed
US-4831190-A BACTERICIDE INTERMEDIATES UBE INDUSTRIES, LTD. (JP) 1989-05-16 US disclosed
JP-S646235-A 3-HYDROXY-2,4,5-TRIFLUOROBENZOIC ACID NIPPON CATALYTIC CHEM IND 1989-01-10 JP disclosed
JP-S63264439-A PRODUCTION OF 3,5,6-TRIFLUORO-4-HYDROXYPHTHALIC ACID UBE IND LTD 1988-11-01 JP disclosed
EP-0271275-A1 Trifluorohydroxyaromatic acid and preparation thereof UBE INDUSTRIES, LTD. (JP) 1988-06-15 EP disclosed
EP-0271275-A1 Trifluorohydroxyaromatic acid and preparation thereof UBE INDUSTRIES, LTD. (JP) 1988-06-15 EP disclosed