Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 2/20 | 0.39 |
| ▸ | LDHB | P07195 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.34 |
| ▸ | GLRB | P48167 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374326 | 0.91 | LDHA (0.39) | ESR1LDHALDHBMEN1KMT2A | |
| SCHEMBL29773954 | 0.87 | ESR1 (0.39) | ESR1LDHALDHBMEN1KMT2A | |
| SCHEMBL7579018 | 0.87 | ESR1 (0.39) | ESR1LDHALDHBMEN1KMT2A | |
| SCHEMBL22279446 | 0.86 | LDHA (0.39) | LDHALDHBMEN1KMT2ACRHBP | |
| Water SCHEMBL9861421 | 0.85 | ESR1 (0.38) | ESR1MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL28924074 | 0.85 | ESR1 (0.38) | ESR1MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL721202 | 0.85 | ESR1 (0.41) | ESR1LDHALDHBMEN1KMT2A | |
| SCHEMBL5586912 | 0.84 | LDHA (0.42) | LDHALDHBMEN1KMT2ACRHBP | |
| Water SCHEMBL1285779 | 0.82 | ESR1 (0.39) | ESR1LDHALDHBMEN1KMT2A | |
| SCHEMBL2011531 | 0.82 | MEN1 (0.46) | MEN1KMT2ACRHBPCRHR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525258-A | LOW VISCOSITY, SHORT RESPONSE TIME | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |