Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721202 | 0.95 | ESR1 (0.41) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| SCHEMBL29773954 | 0.92 | ESR1 (0.39) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| SCHEMBL7579018 | 0.92 | ESR1 (0.39) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| Water SCHEMBL1285779 | 0.92 | ESR1 (0.39) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| SCHEMBL28924074 | 0.90 | ESR1 (0.38) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| Water SCHEMBL9861421 | 0.90 | ESR1 (0.38) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| SCHEMBL28209911 | 0.89 | DPP4 (0.37) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| SCHEMBL31021584 | 0.86 | DPP4 (0.36) | ESR1KMT2ADPP4CA12CA1 | |
| SCHEMBL1899129 | 0.86 | MEN1 (0.37) | ESR1MEN1KMT2ASMN1; SMN2CRHBP | |
| SCHEMBL203915 | 0.86 | CES2 (0.43) | MEN1KMT2ASMN1; SMN2CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757028-B1 | Process for the preparation of aromatic carbonic acid esters | CLARIANT GMBH (DE) | 1999-12-29 | — | — | EP | disclosed |
| US-5874608-A | Process for the preparation of esters of aromatic carboxylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |
| US-5744628-A | Process for the preparation of esters of aromatic carboxylic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| EP-0811601-A1 | Process for the preparation of aromatic carbonic acid esters | Clariant GmbH (DE) | 1997-12-10 | — | — | EP | disclosed |
| EP-0757028-A1 | Process for the preparation of aromatic carbonic acid esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-02-05 | — | — | EP | disclosed |