Nicosulfuron

Nicosulfuron

SCHEMBL7579382

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2ncccc2C(=O)N(C)C)n1.CS(=O)(=O)NC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].O=C(O)CNCP(=O)(O)O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
TTR P02766 1/20 0.40
PPOX P50336 1/20 0.40
KMT2A Q03164 1/20 0.40
CDK1 P06493 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.32
LMNA P02545 2/20 0.32
SCN9A Q15858 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP3A4 P08684 1/20 0.30
UGCG Q16739 1/20 0.30
POLB P06746 1/20 0.30
MAPT P10636 1/20 0.30
CCR6 P51684 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
GPR55 Q9Y2T6 1/20 0.30
FBP1 P09467 1/20 0.30
RAF1 P04049 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nicosulfuron SCHEMBL7582160 0.96 TDP1 (0.39) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7584990 0.95 TDP1 (0.45) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7581535 0.93 MEN1 (0.37) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7589904 0.93 MEN1 (0.34) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7577751 0.93 MEN1 (0.38) TDP1MEN1TTRPPOXKMT2A
Rimsulfuron SCHEMBL7584951 0.92 TDP1 (0.40) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7582557 0.91 TDP1 (0.44) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7588238 0.91 TDP1 (0.37) TDP1MEN1TTRPPOXKMT2A
Nicosulfuron SCHEMBL7582837 0.90 MEN1 (0.33) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7589898 0.90 TDP1 (0.37) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.