Oxyfluorfen

Oxyfluorfen

SCHEMBL7579541

CCNc1nc(NC(C)C)nc(SC)n1.CCOc1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
TTR P02766 1/20 0.45
PPOX P50336 1/20 0.45
HTT P42858 4/20 0.37
MAPT P10636 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALDH1A1 P00352 3/20 0.36
HPGD P15428 2/20 0.36
GAA P10253 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
ATM Q13315 1/20 0.36
TSHR P16473 2/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyfluorfen SCHEMBL7583144 0.96 MEN1 (0.48) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7581668 0.93 KMT2A (0.47) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7581126 0.91 KMT2A (0.46) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7578913 0.87 MEN1 (0.52) KMT2AMEN1TDP1TTRPPOX
Ametryne SCHEMBL7581142 0.85 KMT2A (0.48) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7583985 0.83 KMT2A (0.44) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7575419 0.83 MEN1 (0.48) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7584174 0.83 KMT2A (0.42) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7584789 0.81 MEN1 (0.42) KMT2AMEN1TDP1TTRPPOX
Oxyfluorfen SCHEMBL7581108 0.81 KMT2A (0.42) KMT2AMEN1TDP1TTRPPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT KMT2A 2099/4885MEN1 4274/4885TDP1 1969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.