Mecoprop

Mecoprop

SCHEMBL7579675

CCOC(=O)COC(=O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-].Cc1cc(Cl)ccc1OC(C)C(=O)O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.55
MEN1 O00255 1/20 0.55
TTR P02766 1/20 0.55
PPOX P50336 1/20 0.55
KMT2A Q03164 1/20 0.55
TSHR P16473 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42
FFAR1 O14842 2/20 0.41
ALDH1A1 P00352 1/20 0.40
PTGDR2 Q9Y5Y4 3/20 0.40
MAPT P10636 3/20 0.38
RECQL P46063 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.37
PLA2G1B P04054 1/20 0.36
ATG4B Q9Y4P1 1/20 0.36
LMNA P02545 1/20 0.36
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mecoprop SCHEMBL7581136 0.89 KMT2A (0.45) TDP1MEN1TTRPPOXKMT2A
SCHEMBL38860 0.88 MEN1 (0.68) TDP1MEN1TTRPPOXKMT2A
SCHEMBL7589695 0.88 MEN1 (0.58) TDP1MEN1TTRPPOXKMT2A
Diclofop-Methyl SCHEMBL7588810 0.87 TDP1 (0.55) TDP1MEN1TTRPPOXKMT2A
SCHEMBL10536730 0.87 MEN1 (0.67) TDP1MEN1TTRPPOXKMT2A
Bifenox SCHEMBL7575733 0.87 TDP1 (0.67) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7578255 0.86 TDP1 (0.75) TDP1MEN1TTRPPOXKMT2A
SCHEMBL8534878 0.86 MEN1 (0.66) TDP1MEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7576253 0.86 MEN1 (0.54) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7577659 0.86 MEN1 (0.59) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.