Primisulfuron

Primisulfuron

SCHEMBL7579710

CCS(=O)(=O)c1cccnc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1.COC(=O)c1cc(Oc2ccc(Cl)cc2Cl)ccc1[N+](=O)[O-].O=C(Nc1nc(OC(F)F)cc(OC(F)F)n1)NS(=O)(=O)c1ccccc1C(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.45
MEN1 O00255 1/20 0.34
TTR P02766 1/20 0.34
PPOX P50336 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.33
TBXA2R P21731 4/20 0.32
ROCK2 O75116 1/20 0.32
GAA P10253 1/20 0.32
PPARG P37231 1/20 0.32
BCL2L1 Q07817 1/20 0.31
MCL1 Q07820 1/20 0.31
JMJD7 P0C870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Primisulfuron SCHEMBL7582154 0.94 TDP1 (0.39) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7578675 0.93 TDP1 (0.39) TDP1
Primisulfuron SCHEMBL7582088 0.92 TDP1 (0.38) TDP1
Primisulfuron SCHEMBL7588711 0.92 TDP1 (0.44) TDP1MEN1TTRPPOXKMT2A
Rimsulfuron SCHEMBL7581824 0.91 TDP1 (0.54) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7590931 0.91 TDP1 (0.46) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7581541 0.91 TDP1 (0.55) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7588901 0.88 TDP1 (0.42) TDP1MEN1TTRPPOXKMT2A
Primisulfuron SCHEMBL7587423 0.88 TDP1 (0.40) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7590183 0.88 TDP1 (0.40) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.