Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20302447 | 0.87 | ACHE (0.49) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL20298363 | 0.86 | KDM4E (0.42) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL19023139 | 0.84 | ACHE (0.41) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL19037342 | 0.84 | KDM4E (0.47) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL20298364 | 0.84 | GAA (0.47) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL22833387 | 0.83 | GAA (0.49) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL20298317 | 0.83 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL25501785 | 0.83 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL20560379 | 0.82 | CASP1 (0.54) | SMN1; SMN2MAPTL3MBTL1KDM4EACHE | |
| SCHEMBL20298328 | 0.82 | KDM4E (0.39) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025007784-A1 | HETEROAROMATIC RING COMPOUND, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2025-01-09 | — | — | WO | disclosed |
| CN-112574199-B | Heterocyclic compounds as Kras-G12C inhibitors | 首药控股(北京)股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112574199-A | Heterocyclic compounds as Kras-G12C inhibitors | 首药控股(北京)股份有限公司 | 2021-03-30 | — | — | CN | disclosed |
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | NQO2, NQO1, NDUFA7 | SMN1; SMN2 3221/4885NPC1 215/4885RAB9A 794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.