Acifluorfen

Acifluorfen

SCHEMBL7579790

COc1cc(OC)nc(NC(=O)NS(=O)(=O)c2c(C(=O)O)cnn2C)n1.O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 1/20 0.56
TTR P02766 1/20 0.56
PPOX P50336 1/20 0.56
KMT2A Q03164 1/20 0.56
GAA P10253 1/20 0.38
PYGL P06737 1/20 0.36
TBXA2R P21731 3/20 0.34
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
CCR6 P51684 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
KDR P35968 2/20 0.33
SCN9A Q15858 1/20 0.33
FLT1 P17948 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fomesafen SCHEMBL7581657 0.95 TDP1 (0.51) TDP1MEN1TTRPPOXKMT2A
Oxyfluorfen SCHEMBL7590444 0.93 MEN1 (0.47) TDP1MEN1TTRPPOXKMT2A
SCHEMBL7581595 0.91 TDP1 (0.47) TDP1MEN1TTRPPOXKMT2A
Halosulfuron SCHEMBL7585865 0.90 TDP1 (0.56) TDP1MEN1TTRPPOXKMT2A
Lactofen SCHEMBL7579555 0.90 TDP1 (0.46) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7583316 0.90 TDP1 (0.49) TDP1MEN1TTRPPOXKMT2A
Bifenox SCHEMBL7577737 0.88 TDP1 (0.55) TDP1MEN1TTRPPOXKMT2A
Flupyrsulfuron SCHEMBL7581127 0.86 TDP1 (0.59) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7593293 0.86 TDP1 (0.60) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL7577278 0.86 TDP1 (0.53) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT TDP1 1969/4885MEN1 4274/4885TTR 1945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.