SCHEMBL757988

SCHEMBL757988

C=CCNS(=O)(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
LMNA P02545 2/20 0.55
KEAP1 Q14145 2/20 0.55
KDM4E B2RXH2 1/20 0.55
PKM P14618 1/20 0.55
GPR55 Q9Y2T6 1/20 0.51
GBA1 P04062 2/20 0.50
MAPK1 P28482 2/20 0.50
TSHR P16473 1/20 0.50
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
MMP1 P03956 1/20 0.47
MMP2 P08253 1/20 0.47
MMP9 P14780 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
MEN1 O00255 1/20 0.46
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL4557832 0.98 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAKEAP1KDM4E
SCHEMBL11512411 0.98 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2LMNAKEAP1KDM4E
SCHEMBL7747811 0.83 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2LMNAKEAP1KDM4E
SCHEMBL11666557 0.82 TSHR (0.53) ALDH1A1SMN1; SMN2PKMGPR55MAPK1
SCHEMBL28388371 0.82 SMN1; SMN2 (0.51) ALDH1A1SMN1; SMN2LMNAKEAP1KDM4E
SCHEMBL23088821 0.82 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2LMNAKEAP1KDM4E
SCHEMBL3934921 0.82 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNAKEAP1KDM4E
SCHEMBL4806739 0.81 SIGMAR1 (0.54) ALDH1A1SMN1; SMN2MAPK1TSHRCA1
SCHEMBL4805839 0.81 SIGMAR1 (0.53) ALDH1A1SMN1; SMN2GPR55MAPK1TSHR
SCHEMBL4775427 0.81 CYP3A4 (0.58) ALDH1A1SMN1; SMN2MAPK1TSHRCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118791776-B Activator for improving activity of rubber powder of waste tires and preparation method thereof 太行城乡建设集团有限公司 2024-12-10 CN claimed
CN-118791776-A Activator for improving activity of rubber powder of waste tires and preparation method thereof 太行城乡建设集团有限公司 2024-10-18 CN claimed
WO-2023226515-A1 MXENE-BASED COMPOSITE CONDUCTIVE PASTE, AND PREPARATION METHOD THEREFOR AND USE THEREOF 江苏奥煋新材料科技有限公司 2023-11-30 WO claimed
CN-114990589-B Method for synthesizing beta-amino alcohol compound through 1, 2-ammoxidation 江西师范大学 2023-06-27 CN claimed
CN-113563239-B Preparation method of N-allylbenzenesulfonimide compound 温州大学 2023-05-09 CN claimed
CN-114349668-A Preparation method of N-allyl benzene sulfonamide compound 寿光诺盟化工有限公司 2022-04-15 CN claimed
CN-110818647-A Preparation method of heptatomic ring urea compound 中国石油大学(华东) 2020-02-21 CN claimed
EP-3127937-B1 FLAME RESISTANT POLYAMIDE 12 SUBSTANCES FOR RAIL APPLICATIONS EMS PATENT AG (CH) 2018-03-07 EP claimed
CN-106433106-A Flame-retardant polyamide 12 moulding composition for railway applications EMS 专利股份公司 2017-02-22 CN claimed
US-20170037198-A1 FLAME-RETARDANT POLYAMIDE 12 MOULDING COMPOSITION FOR RAILWAY APPLICATIONS EMS-PATENT AG (CH) 2017-02-09 US claimed
US-4820346-A Ink jet printer ink HOWTEK, INC. (US) 1989-04-11 US claimed
EP-0285946-A2 N-alkyl-benzene sulfonamides BAYER AG (DE) 1988-10-12 EP claimed
EP-0073875-B1 AZO DYESTUFFS, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1988-09-07 EP claimed
EP-0190105-A2 Herbicidal agent CIBA-GEIGY AG (CH) 1986-08-06 EP claimed
EP-0073876-B1 PROCESS FOR THE PRODUCTION OF RESERVE PRINTS ON POLYESTER OR POLYESTER CELLULOSE BLENDED TEXTILES CASSELLA Aktiengesellschaft (DE) 1985-12-11 EP claimed
US-4420308-A Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group CASSELLA AKTIENGESELLSCHAFT (DE) 1983-12-13 US claimed
EP-0073875-A2 Azo dyestuffs, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1983-03-16 EP claimed
EP-0073876-A1 Process for the production of reserve prints on polyester or polyester cellulose blended textiles CASSELLA Aktiengesellschaft (DE) 1983-03-16 EP claimed
US-4300897-A SAFE FOR DYED FABRICS; ALSO CONTAINS AN AROMATIC SULFONAMIDE COLGATE-PALMOLIVE COMPANY (US) 1981-11-17 US claimed
US-4051052-A Liquid developer MITA INDUSTRIAL COMPANY LTD. (JA) 1977-09-27 US claimed