Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320947 | 0.82 | NPSR1 (0.38) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL757988 | 0.81 | ALDH1A1 (0.55) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| Formaldehyde SCHEMBL4557832 | 0.79 | ALDH1A1 (0.53) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11512411 | 0.79 | ALDH1A1 (0.53) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| Methane SCHEMBL27510560 | 0.79 | ALDH1A1 (0.53) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11666557 | 0.79 | TSHR (0.53) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4775427 | 0.78 | CYP3A4 (0.58) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL561968 | 0.78 | NPSR1 (0.62) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4805839 | 0.78 | SIGMAR1 (0.53) | TSHRMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11286912 | 0.78 | SMN1; SMN2 (0.52) | TSHRMAPK1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4247479-A | REACTING THE OXIME HYDROCHLORIDE WITH THREE MOLES OF ACETIC ANHYDRIDE | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-01-27 | — | — | US | claimed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| EP-1663192-A1 | ERG CHANNEL OPENERS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | Poseidon Pharmaceuticals A/S (DK) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005023237-A1 | ERG CHANNEL OPENERS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-03-17 | — | — | WO | disclosed |
| WO-2005023238-A1 | ERG CHANNEL OPENERS FOR THE TREATMENT OF HYPEREXCITABILITY-RELATED NEURONAL DISEASES | POSEIDON PHARMACEUTICALS A/S (DK) | 2005-03-17 | — | — | WO | disclosed |
| US-4734349-A | THERMOPLASTIC ELECTROSTATOGRAPHIC TONERS | EASTMAN KODAK COMPANY (US) | 1988-03-29 | — | — | US | disclosed |