Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341263 | 0.82 | SLC9A1 (0.43) | SLC9A1MCL1MEN1KMT2ANPC1 | |
| SCHEMBL3714299 | 0.81 | MCL1 (0.58) | SLC9A1MCL1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8495806 | 0.80 | MCL1 (0.56) | SLC9A1MCL1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8687275 | 0.75 | CLK1 (0.51) | ITGB3ITGA2BMCL1THRBMEN1 | |
| Hydrochloric Acid SCHEMBL8687228 | 0.74 | KDM4E (0.59) | ITGB3ITGA2BTHRBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8687052 | 0.74 | RXFP1 (0.62) | MEN1KMT2ARXFP1PHGDHHDAC1 | |
| Hydrochloric Acid SCHEMBL8687313 | 0.72 | L3MBTL1 (0.65) | ITGB3ITGA2BTHRBMEN1KMT2A | |
| SCHEMBL6798160 | 0.72 | GAA (0.39) | SLC9A1ITGB3ITGA2BMCL1THRB | |
| SCHEMBL6798165 | 0.70 | GALR3 (0.38) | SLC9A1ITGB3ITGA2BGALR3GAA | |
| SCHEMBL3339080 | 0.70 | SLC9A1 (0.43) | SLC9A1MCL1THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1238971-A1 | SUBSTITUTED GUANIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-09-11 | — | — | EP | disclosed |