Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294778 | 1.00 | TP53 (0.31) | TP53 | |
| SCHEMBL7583745 | 0.93 | — | — | |
| SCHEMBL7589121 | 0.92 | MEN1 (0.35) | — | |
| SCHEMBL18294773 | 0.92 | MEN1 (0.35) | — | |
| SCHEMBL7585843 | 0.88 | — | — | |
| SCHEMBL18294769 | 0.88 | — | — | |
| SCHEMBL13053906 | 0.88 | TP53 (0.34) | TP53 | |
| SCHEMBL7568619 | 0.88 | TP53 (0.34) | TP53 | |
| SCHEMBL7581538 | 0.86 | AKR1A1 (0.33) | — | |
| SCHEMBL7581116 | 0.85 | TP53 (0.31) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183252-B2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-22 | — | — | US | disclosed |