Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18294770 | 0.92 | — | — | |
| SCHEMBL7585494 | 0.92 | — | — | |
| SCHEMBL7580536 | 0.91 | NPY5R (0.34) | — | |
| SCHEMBL7589846 | 0.90 | — | — | |
| SCHEMBL7589926 | 0.88 | NR1H3 (0.30) | — | |
| SCHEMBL7589827 | 0.87 | P2RX7 (0.34) | TP53 | |
| SCHEMBL13054757 | 0.86 | TP53 (0.34) | TP53 | |
| SCHEMBL7581539 | 0.86 | TP53 (0.34) | TP53 | |
| SCHEMBL7589834 | 0.86 | KIF11 (0.38) | — | |
| SCHEMBL18294778 | 0.85 | TP53 (0.31) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183252-B2 | Heterocyclic aspartyl protease inhibitors | SCHERING CORPORATION (US) | 2012-05-22 | — | — | US | disclosed |