Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347770 | 0.86 | KMT2A (0.63) | KMT2APGRCYP19A1ARHPGD | |
| SCHEMBL4354395 | 0.83 | KMT2A (0.62) | KMT2APGRCYP19A1ARHPGD | |
| SCHEMBL359651 | 0.81 | KMT2A (0.69) | KMT2APGRCYP19A1ARHPGD | |
| Hydrochloric Acid SCHEMBL5794620 | 0.80 | KMT2A (0.97) | KMT2APGRCYP19A1ARHPGD | |
| SCHEMBL633995 | 0.79 | KMT2A (0.76) | KMT2APGRCYP19A1ARHPGD | |
| SCHEMBL15848296 | 0.79 | RAB9A (0.56) | KMT2AHPGDHDAC1MEN1ALDH1A1 | |
| SCHEMBL18423435 | 0.78 | HPGD (0.53) | KMT2APGRARHPGDMEN1 | |
| SCHEMBL9478969 | 0.77 | KMT2A (0.59) | KMT2APGRCYP19A1ARHPGD | |
| SCHEMBL9479374 | 0.76 | KMT2A (0.72) | KMT2APGRCYP19A1ARHPGD | |
| SCHEMBL11372811 | 0.76 | KMT2A (0.72) | KMT2APGRCYP19A1ARHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |