Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580291 | 1.00 | FFAR1 (0.35) | FFAR1PIN1LMNAL3MBTL1CA2 | |
| SCHEMBL7571250 | 0.76 | CYP1A2 (0.45) | LMNAL3MBTL1CA2G6PC1CA1 | |
| SCHEMBL7571246 | 0.76 | CYP1A2 (0.45) | LMNAL3MBTL1CA2G6PC1CA1 | |
| SCHEMBL7573431 | 0.76 | HPGD (0.33) | LMNAL3MBTL1CA2NPC1RAB9A | |
| SCHEMBL7582036 | 0.76 | CA2 (0.33) | LMNAL3MBTL1CA2CA1TAAR1 | |
| SCHEMBL7573127 | 0.76 | CA2 (0.33) | LMNAL3MBTL1CA2CA1MAPT | |
| SCHEMBL7573436 | 0.76 | HPGD (0.33) | LMNAL3MBTL1CA2NPC1RAB9A | |
| SCHEMBL7575256 | 0.76 | G6PC1 (0.35) | LMNAL3MBTL1CA2G6PC1CA1 | |
| SCHEMBL7575258 | 0.76 | G6PC1 (0.35) | LMNAL3MBTL1CA2G6PC1CA1 | |
| SCHEMBL7573124 | 0.76 | CA2 (0.33) | LMNAL3MBTL1CA2CA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |