Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MELK | Q14680 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580453 | 1.00 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KDM4EASIC3RELA | |
| SCHEMBL7571171 | 0.89 | KDM4E (0.40) | L3MBTL1ALDH1A1KDM4EASIC3RELA | |
| SCHEMBL7571168 | 0.89 | KDM4E (0.40) | L3MBTL1ALDH1A1KDM4EASIC3RELA | |
| SCHEMBL7579129 | 0.86 | CHRM5 (0.43) | L3MBTL1ALDH1A1KDM4ECYP1A2LMNA | |
| SCHEMBL7579120 | 0.86 | CHRM5 (0.43) | L3MBTL1ALDH1A1KDM4ECYP1A2LMNA | |
| SCHEMBL7575183 | 0.83 | IKBKB (0.48) | ALDH1A1KDM4ECYP1A2LMNAGAA | |
| SCHEMBL7571246 | 0.82 | CYP1A2 (0.45) | L3MBTL1ALDH1A1KDM4ECYP1A2LMNA | |
| SCHEMBL7571250 | 0.82 | CYP1A2 (0.45) | L3MBTL1ALDH1A1KDM4ECYP1A2LMNA | |
| SCHEMBL7572739 | 0.81 | MEN1 (0.49) | ALDH1A1KDM4ELMNACA2GAA | |
| SCHEMBL7573370 | 0.80 | MAPT (0.35) | L3MBTL1ALDH1A1KDM4EASIC3CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |