Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7580519 | 1.00 | MAPT (0.39) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7571819 | 0.87 | CYP1A2 (0.39) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7571823 | 0.87 | CYP1A2 (0.39) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7571835 | 0.82 | CHRM5 (0.43) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7581260 | 0.82 | LMNA (0.38) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7571831 | 0.82 | CHRM5 (0.43) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7573242 | 0.82 | MEN1 (0.37) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7573246 | 0.82 | MEN1 (0.37) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7579739 | 0.79 | LMNA (0.43) | MAPTKMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL7579742 | 0.79 | LMNA (0.43) | MAPTKMT2ACYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |